Addition of Pycnogenol® to troxerutin enhances significantly efficacy of treatment and prolongs symptom relief.
Riccioni, C., Sarcinella, R., Izzo, A., Palermo, G., and Lignori, L. (2004)Efficacy of Troxerutine in association with Pycnogenol® in the treatment of venous insufficiencyEuropean Bulletin of Drug Research, 12 (1): 7-12