

Their flagship ingredient, Pycnogenol®, is constantly being tested by product development against new and evolving research.
Since Pycnogenol® is derived from a consistent and reliable source, you can expect Pycnogenol product formulas to be of exceptional quality. Below are examples of exclusive, finished products and product lines recently introduced to consumers around the world.
| Cardiovascular Health solution | |
PycnoQ10®: | ![]() |
CoQ10+: |
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Paleno®: |
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| Beauty Cosmetic Solutions | |
Restgenol®: Pycnogenol® is included in many cosmetic products because of its proven research in maintaining healthy skin. Studies found that Pycnogenol® acts as a collagen stabilizer by binding to collagen in the skin and maintaining elasticity, saving it from destruction. This action helps keep the skin firm and prevents wrinkles. The antioxidant also improves microcirculation of tiny skin capillaries which help support better oxygen, nutrient and hydration supplies to the skin. The top selling anti-aging cosmetic Restgenol® line is sold exclusively through Sony beauty shops and esthetic salons in Japan. | ![]() |
Evelle®: Product ingredients include antioxidant Pycnogenol® that stabilizes and protects collagen and elastin in the skin and Bio-Marine Complex with proteins and polysaccharides, to help improve the structure and quality of the dermis resulting in smoother, suppler skin. Plant extracts with lycopene and anthoocyanidins contribute natural antioxidant benefits. Evelle® is available in the United Kingdom, Austria, Hungary, Sweden, Thailand and Japan. |
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Derma e® Eye Lighten Dark Circle Crème: |
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Iklen® Pycnogenol®: According to clinical research on Pycnogenol, the botanical extract helps reduce the appearance of brown spots for clearer, spot free skin. Additional research on Pycnogenol’s photo-aging properties demonstrates its ability to increase skin photo protection by inhibiting inflammation which occurs in response to environmental factors like ultraviolet (UV) light exposure. The essential oils in Iklen help restore skin flexibility and tonicity. Merck recommends taking one or two caplets a day for optimal results either alone or in association with a dermatological treatment. |
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Un Destino: There are six products containing Pycnogenol® in the Un Destino beauty line and they include an oral skin health and beauty supplement called Sabinna, a drink supplement, tonifying face cream, oil-free face cleansing gel, face and body soap and moisturizing lotion. Each beauty product contains Pycnogenol for optimal antioxidant protection and other ingredients like placenta extract, tocotrienols, vitamin E and hyaluronic acid. Pycnogenol is a versatile super antioxidant and has an abundance of skin and beauty health benefits. Studies have demonstrated that Pycnogenol® acts as a collagen stabilizer by binding to collagen in the skin and maintaining elasticity, saving it from destruction. This action helps keep the skin firm and prevents wrinkles. It also improves microcirculation of tiny skin capillaries which help support better oxygen, nutrient and hydration supplies to the skin. |
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YZ Formula SP: |
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Silicium: |
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| Eye Health Solutions | |
Lutegenol™: Scientists have found that lutein, a carotenoid found in dark, green leafy vegetables and certain fruits, plays a beneficial role in eye health by helping reduce the risk of age-related macular degeneration (AMD). AMD is caused when the macula of the eye deteriorates from a lifetime of steady damage due to oxidative stress in the retina. This causes the gradual loss of central vision and patient symptoms vary depending on if they suffer from dry or wet AMD. Pycnogenol® research indicates that its properties best protect the eye by keeping blood vessels and capillaries functioning efficiently, especially in diabetics who are prone to diabetic retinopathy. Diabetic retinopathy is a leading cause of blindness in people under the age of 60 and occurs when elevated glucose levels in the blood react within the capillaries of the retina, resulting in swollen and brittle walls that eventually lead to blood leaking into the retina causing gradual vision loss. |
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| Menstrual Health Solutions | |
Benefique:
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| Functional Beverage Solutions | |
One-A-Night: The product is available on the Otsuka website and in supermarkets and convenience stores in Hiroshima prefecture. An integrated television advertising and public relations campaign is in place to introduce the products and educate consumers on their unique health benefits.
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| Sexual Wellness Solutions | |
Prelox®:
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FertilOx: |
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| Travel Health Solutions | |
Zinopin®: |
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